发明名称 |
DISINTEGRANT-FREE DELAYED RELEASE DOXYLAMINE AND PYRIDOXINE FORMULATION AND PROCESS OF IT MANUFACTURING |
摘要 |
The present invention relates to a delayed release pharmaceutical composition containing doxylamine succinate and pyridoxine HCl for treatment of nausea and vomiting during pregnancy. More specifically, the present invention concerns a disintegrant-free delayed release pharmaceutical composition for oral administration comprising a core and an enteric coating, wherein said core comprising: a) at least one pharmaceutically active ingredient, and b) at least one pharmaceutically acceptable excipient, wherein said composition provides an in vitro drug release profile of about 80% of active ingredient dissolved within 20 minutes as measured by USP Type II apparatus and also a manufacturing process of said pharmaceutical composition. |
申请公布号 |
CA2761212(A1) |
申请公布日期 |
2013.06.07 |
申请号 |
CA20112761212 |
申请日期 |
2011.12.07 |
申请人 |
PHARMASCIENCE INC. |
发明人 |
MA, DAVID;MANDAOGADE, PRASHANT MANOHAR;TALWAR, NARESH |
分类号 |
A61K9/22;A61K31/4402;A61K31/4415 |
主分类号 |
A61K9/22 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|