PHARMACEUTICAL COMPOSITION COMPRISING EXTRACT OF SECURINEGA SUFFRUCTICOSA SHOWING AN INHIBITORY EFFECT OF OSTEOCLASTOGENESIS

摘要

PURPOSE: A pharmaceutical composition containing a Securinega suffruticosa extract is provided to effectively suppress osteoclast activity and to treat bone diseases due to menopause or senile bone diseases. CONSTITUTION: A pharmaceutical composition for preventing and treating metabolic bone diseases contains a Securinega suffruticosa extract as an active ingredient, which suppresses osteoporosis. The metabolic bone diseases are osteoporosis, Paget's disease, periodontal disease, metastatic cancer, or rheumatoid arthritis. The extract contains 0.01-99wt% of a crude drug extract.