发明名称 |
ACTIVITY BASED PROBES (ABPs) INTERACTING WITH GLYCOSIDASES |
摘要 |
An activity based probe (ABP) comprising a glycosidase inhibitor, and a detection-group. The ABPs of the inventions are used for diagnosing storage disorder for screening of compounds suitable for preventing and/or treating a storage disorder, for monitoring of therapeutic enzymes for lysosomal storage disorders, and for ultra-sensitive visualization of glycosidase-fusion proteins in molecular imaging.
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申请公布号 |
US2013143228(A1) |
申请公布日期 |
2013.06.06 |
申请号 |
US201113583193 |
申请日期 |
2011.03.10 |
申请人 |
AERTS JOHANNES MARIA FRANCISCUS GERARDUS;OVERKLEEFT HERMAN STEVEN |
发明人 |
AERTS JOHANNES MARIA FRANCISCUS GERARDUS;OVERKLEEFT HERMAN STEVEN |
分类号 |
C07D303/14;C07D203/26;C07D303/36;C07F5/02 |
主分类号 |
C07D303/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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