Population of hematopoietic progenitors and methods of enriching stem cells therefor

摘要

There is described herein a method of enriching a population of stem cells for hematopoietic progenitors. The method comprises inducing hematopoietic differentiation in a population of human embryonic stem cells or human induced 5 pluripotent stem cells; sorting the population based on expression of CD43 and at least one of CD34, CD31 and CD144; and selecting a fraction that is at least one of CD34*CD43', CD31*CD43- and CD144*CD43-. Also provided are populations of hematopoietic progenitors obtained by the methods described herein.