发明名称 |
QUINOXALINE-CONTAINING COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS |
摘要 |
The present invention discloses compounds of formula I and II or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
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申请公布号 |
US2013144036(A1) |
申请公布日期 |
2013.06.06 |
申请号 |
US201213657555 |
申请日期 |
2012.10.22 |
申请人 |
ENANTA PHARMACEUTICALS, INC.;ENANTA PHARMACEUTICALS, INC. |
发明人 |
GAI YONGHUA;OR YAT SUN;WANG ZHE |
分类号 |
A61K38/12;C07K5/08;C07K5/10;C07K5/113;C07K5/12 |
主分类号 |
A61K38/12 |
代理机构 |
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地址 |
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