The invention relates to the identification of new polypeptide and protein variants of fibroblast growth factor 21 (FGF21) that have improved pharmaceutical properties. Also disclosed are methods for treating FGF21-associated disorders, including metabolic conditions.
申请公布号
AU2011331166(A1)
申请公布日期
2013.06.06
申请号
AU20110331166
申请日期
2011.11.17
申请人
IRM LLC;NOVARTIS AG
发明人
BOETTCHER, BRIAN R.;CAPLAN, SHARI L.;DANIELS, DOUGLAS S.;GEIERSTANGER, BERNHARD H.;HAMAMATSU, NORIO;LICHT, STUART;LOEW, ANDREAS;WELDON, STEPHEN CRAIG
