发明名称 |
Process for the Production of Seven-Membered Lactam Morphinans |
摘要 |
The present invention relates to improved processes for preparing lactam morphinans. The processes generally transform keto-morphinans to seven-membered lactam morphinans using a hydroxyamine sulfonic acid reagent and proceed in high yield and with good selectivity.
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申请公布号 |
US2013144053(A1) |
申请公布日期 |
2013.06.06 |
申请号 |
US201213705205 |
申请日期 |
2012.12.05 |
申请人 |
MALLINCKRODT LLC;MALLINCKRODT LLC |
发明人 |
GROTE CHRISTOPHER W.;MCCLURG JOSEPH P.;MOSER FRANK W. |
分类号 |
C07D491/18 |
主分类号 |
C07D491/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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