发明名称 |
RECOMBINANT INFLUENZA VIRUS-LIKE PARTICLES (VLPS) PRODUCED IN TRANSGENIC PLANTS EXPRESSING HEMAGGLUTININ |
摘要 |
A method for synthesizing influenza virus-like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of influenza HA in plants and the purification by size exclusion chromatography. The invention is also directed towards a VLP comprising influenza HA protein and plant lipids. The invention is also directed to a nucleic acid encoding influenza HA as well as vectors. The VLPs may be used to formulate influenza vaccines, or may be used to enrich existing vaccines.
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申请公布号 |
US2013142826(A1) |
申请公布日期 |
2013.06.06 |
申请号 |
US201313748531 |
申请日期 |
2013.01.23 |
申请人 |
MEDICAGO, INC.;MEDICAGO, INC. |
发明人 |
D'AOUST MARC-ANDRE;COUTURE MANON;ORS FREDERIC;TREPANIER SONIA;LAVOIE PIERRE-OLIVIER;DARGIS MICHELE;VEZINA LOUIS-PHILIPPE;LANDRY NATHALIE |
分类号 |
C12N15/82 |
主分类号 |
C12N15/82 |
代理机构 |
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