摘要 |
<p>The invention relates to a new pharmaceutical compound, diacyl phosphatdylinositol in which both the sn-1 and the sn-2 place are taken by stearic acid (18:0) (diacyl [18:0; 18:0] phosphatidylinositol), more preferably, wherein said diacyl phosphatidylinositol is compound 1 as depicted in Fig. 10 or a racemate of compounds 1 and 2 as depicted in Fig. 10. Said pharmaceutical compound and pharmaceutical compositions comprising this compound are specifically useful for the treatment of a disease or a condition wherein suppression of T-cell activation is desirable, such as asthma, diabetes Type 1, rheumatoid arthritis, inflammatory bowel disease or psoriasis. Also part of the invention are food items containing the compound(s) of the invention and use thereof in a diet to treat or prevent the disease or condition mentioned above</p> |
申请人 |
ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM;SAMSOM, JANNEKE NICOLINE;NIEUWENHUIS, EDWARD EELCO SALOMON;BOESEN, JOHANNES JOSEPHES BERNARDUS |
发明人 |
SAMSOM, JANNEKE NICOLINE;NIEUWENHUIS, EDWARD EELCO SALOMON;BOESEN, JOHANNES JOSEPHES BERNARDUS |