IgA-BINDING PEPTIDE AND PURIFICATION OF IgA THEREBY

摘要

The present invention relates to a peptide which contains an amino acid sequence consisting of 14 to 18 amino acid residues and capable of binding to human IgA, and an analysis or purification method for the human IgA which uses the peptide. The peptide is represented by H-(X1)-V-C-L-S-Y-R-(X2)-(X3)-G-(X4)-P-(X5)-C-(X6)-(X7)-(X8) (I) (sequence number 1) (in the formula, each of the Xs is independently selected from the following: X1 is a Gln residue or a Met residue; X2 and X3 are independently any amino acid residue other than Cys or any one or both sides thereof are deleted; X4 is an Arg residue or the Gln residue; X5 is a Val residue or a Thr residue; X6 is a Phe residue or a Tyr residue; X7 is a Ser residue or null; X8 is a Leu residue, Thr residue, or null [in the case where X1 is the Met residue, X7 is the Ser residue or null, and X8 is null]).