| 发明名称 |
ANTI-CEACAM1 RECOMBINANT ANTIBODIES FOR CANCER THERAPY |
| 摘要 |
Provided herein are recombinant monoclonal antibodies and antigen-binding portions thereof useful in inhibiting CEACAM1 in tumor cells, and methods of their use in anti-tumor proliferation and invasiveness therapies, such as the treatment of cancer, particularly pancreatic cancer. |
| 申请公布号 |
WO2013082366(A1) |
申请公布日期 |
2013.06.06 |
| 申请号 |
WO2012US67207 |
申请日期 |
2012.11.30 |
| 申请人 |
THE BRIGHAM AND WOMEN'S HOSPITAL, INC. |
发明人 |
BLUMBERG, RICHARD S.;HUANG, YU-HWA;UTKU, NALAN |
| 分类号 |
C07K16/28;A61K39/395;A61P35/00;C12N5/10;C12N15/13;C12N15/63;G01N33/53 |
主分类号 |
C07K16/28 |
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