| 发明名称 |
2- (PHENYL OR PYRID - 3 - YL) AMINOPYRIMIDINE DERIVATIVES AS KINASE LRRK2 MODULATORS FOR THE TREATMENT OF PARKINSON'S DISEASE |
| 摘要 |
Compounds of the formula (I), or pharmaceutically acceptable salts thereof, wherein m, n. X, R1, R2, R3, R4 and R5 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with LRRK2 receptor, such as Parkinson's disease. |
| 申请公布号 |
CA2850705(A1) |
申请公布日期 |
2013.06.06 |
| 申请号 |
CA20122850705 |
申请日期 |
2012.11.28 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
BAKER-GLENN, CHARLES;CHAMBERS, MARK;CHAN, BRYAN K.;ESTRADA, ANTHONY;SWEENEY, ZACHARY KEVIN |
| 分类号 |
C07D403/12;A61K31/506;A61P25/16;C07D405/14;C07D413/12;C07D417/12 |
主分类号 |
C07D403/12 |
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