ANTIBODY RECOGNIZING TURN STRUCTURE IN AMYLOID ß

摘要

Provided is a therapeutic method exclusively targeting an amyloid ² protein (A²) having a specific turn structure of A². Specifically provided is an antibody which specifically recognizes an amyloid ² having a turn structure at amino acids positions 22 and 23. Also provided are a medicinal composition comprising, as the active ingredient, an antibody specifically recognizing a toxic conformer of amyloid ², an assay kit for a toxic conformer of amyloid ², a diagnostic for Alzheimer's disease, etc.