| 摘要 |
<p>The invention relates to telmisartan, 2-(4-{[4-methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl]methyl}phenyl) benzoic acid, or a pharmaceutically acceptable salt thereof for use in promoting autophagy. The invention also relates to the use of Telmisartan or a pharmaceutically acceptable salt thereof in the treatment of autophagy related disorders, such as various forms of cancer; liver disease, myopathies of various origin; cardiovascular disorders, neurodegenerative disorders. In addition Telmisartan can be used to extend the capabilities of humans or animals of leading a longer life called longevity. The invention further relates to suitable pharmaceutical compositions, which contain telmisartan as a combined preparation for simultaneous, separate or sequential use for the treatment and prevention of these diseases.</p> |
