摘要 |
<p>The present invention relates to an interchangeable disposable measuring cassette for insertion into a measuring apparatus for detecting target molecules in a liquid sample by measuring fluorescence emission, wherein the measuring cassette has a flow measurement cell in which an excitation radiation provided by the measuring apparatus produces an evanescent field in the liquid sample beyond a boundary layer for the liquid sample and the measurement cell. In order to be better able to ensure that no sample liquid can cross from the measurement cell into the measuring apparatus, in particular to the fluorescence detector or to the excitation source, the invention proposes that the measuring cassette comprises a body consisting of an optically transparent material and a base in contact with the underside of the body, wherein the measurement cell is formed by a cutout which is provided in the body, in the base or both in the body and in the base, wherein the areas on which the body and the base are on top of one another around this cutout are connected to one another directly and in fluid-tight fashion by means of laser welding.</p> |