发明名称 |
NOVEL NUCLEIC ACID HAVING ADJUVANT ACTIVITY AND USE THEREOF |
摘要 |
<p>The disclosed nucleic acid at least containing a single-stranded DNA to be delivered to endosomes of dendritic cells and a double-stranded RNA capable of activating TLR3 can be delivered to endosomal TLR3 and has a strong adjuvanticity with few side effects, and therefore is useful as an active ingredient of immunostimulants, vaccine adjuvants, cancer therapeutic agents and the like.</p> |
申请公布号 |
EP2599866(A1) |
申请公布日期 |
2013.06.05 |
申请号 |
EP20110812534 |
申请日期 |
2011.07.27 |
申请人 |
NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY |
发明人 |
SEYA, TSUKASA;MATSUMOTO, MISAKO |
分类号 |
C12N15/09;A61K31/713;A61K39/39;A61P37/04;C12N15/117 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|