发明名称 |
METHODS TO IDENTIFY TARGETS AND MOLECULES REGULATING PURINOSOMES AND THEIR USES |
摘要 |
<p>The present invention discloses methods to identify targets, pathways and molecules regulating purinosomes and their uses for treating pathophysiological disorders associated with purinosomes. Disclosed are methods related to both label-free cellular assays and fluorescence imaging to confirm the regulatory roles of various targets and molecules in purinosome dynamics. Disclosed are methods to classify molecules and the uses of these molecules for different indications. Specifically, the purinosome-disrupting molecules can be used for improved prevention and treatment of cancer development.</p> |
申请公布号 |
EP2598146(A1) |
申请公布日期 |
2013.06.05 |
申请号 |
EP20110740760 |
申请日期 |
2011.07.14 |
申请人 |
CORNING INCORPORATED |
发明人 |
BENKOVIC, STEPHEN;FANG, YE;AN, SONGON;VERRIER, FLORENCE |
分类号 |
A61K31/506;G01N33/50 |
主分类号 |
A61K31/506 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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