| 摘要 |
A process for forming superficially porous metal oxide particles, such as silica, is disclosed, where the process comprises hydrolyzing and condensing a metal oxide precursor comprising a functional group, such as 3-mercaptopropyltrimethoxysilane (MPTMS), to form superficially porous metal oxide particles, the superficially porous metal oxide particles comprising metal oxide microparticles having metal oxide nanoparticles bound to the surface of the microparticles. The process may be under alkaline conditions in the presence of ammonium hydroxide. There may be a quaternary ammonium surfactant present. There may be a colloid stavbilising hydrophilic polymer such as PVA or PVP present. The nanoparticles provide a porous outer layer on the microparticles. The superficially porous particles are useful in liquid chromatography and allow for fast mass transfer and separation of samples. The process is conveniently a one-pot synthesis. |
