| 摘要 |
595993 METHOD FOR DIAGNOSIS OF CANCER AND MONITORING OF CANCER TREATMENTS Provided is a method of diagnosis of cancer, comprising the steps of: (a) determining a DNA fragmentation pattern of a repetitive element or multi copy gene represented by 4 to 6 fragments of 80 to 500 bp of said repetitive element or multi copy gene in a body fluid sample isolated from a patient suspected to have cancer, (b) comparing the DNA fragmentation pattern determined in step (a) with a DNA fragmentation pattern of said repetitive element or multi copy gene in reference samples isolated from patients not suffering from cancer and from patients known to have cancer, (c) determining a level of said DNA fragments which are differentially expressed in the sample isolated from the diagnosed patient compared to the reference samples, wherein the level of the DNA fragments, if above a threshold level for cancer patients in the reference samples, indicates that the diagnosed patient is likely to be suffering from cancer.
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