A COMPOSITION FOR INHIBITING THE ACTIVITY OF IMMUNOCYTE

摘要

PURPOSE: A composition for suppressing immunocytes containing a coprisin peptide derivative, CopA3(9-mer disulfide dimer), as an active ingredient is provided to significantly suppress activation of macrophage without side effects such as cytotoxicity, and to develop a novel therapeutic agent for treating immune diseases including arteriosclerosis and rheumatoid arthritis. CONSTITUTION: A composition for suppressing immunocytes contains a coprisin peptide derivative, CopA3(9-mer disulfide dimer), as an active ingredient. The derivative is a regulator which suppresses activation of immunocytes. The immunocytes are macrophage. The derivative is D-type and is derived from an insect. The derivative is used for treating immune diseases including arteriosclerosis and rheumatoid arthritis.