发明名称 |
ANTI-P-SELECTIN ANTIBODIES |
摘要 |
<p>This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor Clq. These antibodies have new and inventive properties causing a benefit for a patient suffering from critical limb ischemia or peripheral arterial occlusive disease (CLI/PAOD).</p> |
申请公布号 |
SI1737891(T1) |
申请公布日期 |
2013.05.31 |
申请号 |
SI20050031695T |
申请日期 |
2005.04.05 |
申请人 |
F.HOFFMANN-LA ROCHE AG |
发明人 |
GRAUS YVO;HIMBER JACQUES;JANSEN-MOLENAAR MIRANDA;KLING DOROTHEE;KOPETZKY ERHARD;PARREN PAUL;REBERS FRANK;STEINER BEAT;STERN ANNE;STREIN PAMELA;STUBENRAUCH KAY-GUNNAR;VAN DE WINKEL JAN;VAN VUGT MARTINE |
分类号 |
A61K39/395;C07K16/28;C07K16/46 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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