| 发明名称 |
PENTABASIC DIHYDROGEN HETEROCYCLIC KETONE DERIVATIVE AS DHODH INHIBITOR AND USE THEREOF |
| 摘要 |
<p>The present invention relates to the synthesis and use of a pentabasic dihydrogen heterocyclic ketone derivative of general formula (I) used as a DHODH inhibitor for Plasmodium falciparum, and the compound related to the present invention can be used for the treatment and prevention of diseases related to DHODH, comprising treatment for parasitic diseases, such as malaria, etc., caused by malaria parasites.</p> |
| 申请公布号 |
WO2013075596(A1) |
申请公布日期 |
2013.05.30 |
| 申请号 |
WO2012CN84556 |
申请日期 |
2012.11.14 |
| 申请人 |
EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY |
发明人 |
LI, HONGLIN;ZHAO, ZHENJIANG;HUANG, JIN;XU, YUFANG;XU, MINGHAO;DIAO, YANYAN;ZHOU, HONGCHANG;JIN, HUANGTAO;GAO, RUI;ZHU, JUNSHENG |
| 分类号 |
C07D307/58;A61K31/341;A61K31/381;A61P13/12;A61P17/06;A61P19/02;A61P29/00;A61P33/06;A61P37/02;A61P37/06;C07D333/32 |
主分类号 |
C07D307/58 |
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