发明名称 |
TUMOR THERAPY WITH REPLICATION COMPETENT SINDBIS VIRAL VECTORS |
摘要 |
Disclosed herein are methods for treating a mammal harboring a solid tumor which expresses higher levels of High Affinity Laminin Receptors (LAMR) than normal cells of the same lineage comprising systematically administering to a mammal in need of such treatment a therapeutically effective amount of a Replication Competent (RC) Sindbis virus vector, wherein said vector encodes a suicide gene.
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申请公布号 |
US2013137754(A1) |
申请公布日期 |
2013.05.30 |
申请号 |
US201213644229 |
申请日期 |
2012.10.03 |
申请人 |
NEW YORK UNIVERSITY;NEW YORK UNIVERSITY |
发明人 |
MERUELO DANIEL;TSENG JEN-CHIEH |
分类号 |
A61K48/00;A61K38/17;C12N15/85;C12N15/86 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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