| 发明名称 |
PROCESS FOR MAKING TRANS-1-((1R,3S)-6-CHLORO-3-PHENYLINDAN-1-YL)-3,3-DIMETHYLPIPERAZINE |
| 摘要 |
Described is a method for making compounds of formula (I) and (IX)comprising racemisation of initial substances using chiral chromatography replacement a spiro group to a removing group, reacting with 2,2-dimethylpiperazine to obtain Compound I and further methylation of the compound of formula I by secondary amine to obtain the compound of formula IX, respectively. |
| 申请公布号 |
EA018059(B1) |
申请公布日期 |
2013.05.30 |
| 申请号 |
EA20070001738 |
申请日期 |
2006.02.14 |
| 申请人 |
H. LUNDBECK A/S |
发明人 |
DAHL ALLAN, CARSTEN;WOEHLK NIELSEN CHRISTINA;SUTEU CHRISTINA;ROBIN DAVID;BROESEN PETER |
| 分类号 |
C07D295/073;C07C49/697 |
主分类号 |
C07D295/073 |
| 代理机构 |
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代理人 |
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| 主权项 |
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