发明名称 |
MURINE MODEL OF INFLAMMATION WITH IL33 N-TERMINAL DOMAIN DELETION. |
摘要 |
<p>The present invention relates to a non-human animal deficient in the N-terminal domain of the IL-33 gene. Also provided herein is the use of said non-human animal as an in vivo model of inflammatory diseases, especially with regard to screening methods for anti-inflammatory compounds, and methods for evaluating and optimising the pharmacological properties of a given anti-inflammatory compound.</p> |
申请公布号 |
MX2013004239(A) |
申请公布日期 |
2013.05.30 |
申请号 |
MX20130004239 |
申请日期 |
2011.10.26 |
申请人 |
F. HOFFMANN-LA ROCHE AG.* |
发明人 |
JAVIER COTE-SIERRA;ANTONIO IGLESIAS;CLAAS AIKO MEYER |
分类号 |
A01K67/027;C12N15/85 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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