发明名称 |
THERAPEUTIC USE OF AGONISTS OR ANTAGONISTS OF BRADYKININ RECEPTOR 1 OR 2, FOR MODULATION COLLATERAL BLOOD VESSEL GROWTH |
摘要 |
The present invention relates to bradykinin receptor modulators and pharmaceutical compositions thereof for use as a medicament for modulating collateral blood vessel growth of collateral arteries and/or other blood vessels of pre-existing arterial networks. The bradykinin receptor modulators of arteriogenesis are applicable in the treatment and/or prevention of disorders associated with defective blood flow or blood vessel malformation. A preferred aspect of the invention relates to bradykinin receptor agonists for use as a medicament for the prevention of cardiovascular ischemic disease in a patient at risk thereof. Further, the invention relates to a bradykinin receptor agonist for use in a method for treating a cardiovascular ischemic disease in a patient in need thereof, wherein said cardiovascular ischemic disease is a peripheral limb disease.
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申请公布号 |
US2013136717(A1) |
申请公布日期 |
2013.05.30 |
申请号 |
US201113697745 |
申请日期 |
2011.05.16 |
申请人 |
HILLMEISTER PHILIPP;BUSCHMANN IVO;LENOBLE FERDINAND;GATZKE NORA;MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN |
发明人 |
HILLMEISTER PHILIPP;BUSCHMANN IVO;LENOBLE FERDINAND;GATZKE NORA |
分类号 |
A61K38/04;A61K45/06 |
主分类号 |
A61K38/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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