| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a composition containing polyamidoamine dendron lipid having a new molecular structure for introducing a nucleic acid. <P>SOLUTION: This composition for introducing a nucleic acid contains a compound expressed by any of formulae DL-G1 to DL-G4. DL-G1 is R<SP POS="POST">1</SP>R<SP POS="POST">2</SP>NX(YH<SB POS="POST">2</SB>)<SB POS="POST">2</SB>. DL-G2 is R<SP POS="POST">1</SP>R<SP POS="POST">2</SP>NX(Y(YH<SB POS="POST">2</SB>)<SB POS="POST">2</SB>)<SB POS="POST">2</SB>. DL-G3 is R<SP POS="POST">1</SP>R<SP POS="POST">2</SP>NX(Y(Y(YH<SB POS="POST">2</SB>)<SB POS="POST">2</SB>)<SB POS="POST">2</SB>)<SB POS="POST">2</SB>. DL-G4 is R<SP POS="POST">1</SP>R<SP POS="POST">2</SP>NX(Y(Y(Y(YH<SB POS="POST">2</SB>)<SB POS="POST">2</SB>)<SB POS="POST">2</SB>)<SB POS="POST">2</SB>)<SB POS="POST">2</SB>. In formulae, X is -CH<SB POS="POST">2</SB>CH<SB POS="POST">2</SB>CONHCH<SB POS="POST">2</SB>CH<SB POS="POST">2</SB>N<; Y is -CH<SB POS="POST">2</SB>CH<SB POS="POST">2</SB>CONH(CH<SB POS="POST">2</SB>)<SB POS="POST">n</SB>N<; n is an integer of 0-6, provided 2 is excluded; R<SP POS="POST">1</SP>and R<SP POS="POST">2</SP>are the same as or different from each other, and saturated or unsaturated long chain aliphatic group. <P>COPYRIGHT: (C)2013,JPO&INPIT |
