发明名称 Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene A4 hydrolase
摘要 Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amine compounds are described, which are useful as LTA4 hydrolase (LTA4H) modulators. Such compounds may be used in pharmaceutical compositions and methods for modulation of LTA4H and for the treatment of disease states, disorders, and conditions mediated by LTA4 hydrolase activity.
申请公布号 AU2013205607(A1) 申请公布日期 2013.05.30
申请号 AU20130205607 申请日期 2013.05.01
申请人 JANSSEN PHARMACEUTICA NV 发明人 BACANI, GENESIS M.;BROGGINI, DIEGO;CHEUNG, EUGENE Y.;CHROVIAN, CHRISTA C.;DENG, XIAOHU;FOURINE, ANNE M.;GOMEZ, LAURENT;GRICE, CHERYL A.;KEARNEY, AARON M.;LANDRY-BAYLE, ADRIENNE M.;LEE-DUTRA, ALICE;LIANG, JIMMY T.;LOCHNER, SUSANNE;MANI, NEELAKANDHA S.;SANTILLAN, ALEJANDRO;SAPPEY, KATHLEEN C.;SEPASSI, KIA;TANIS, VIRGINIA M.;WICKBOLDT, ALVAH T.;WIENER, JOHN J.M.;ZINSER, HARTMUT
分类号 C07D498/04;A61K31/4985 主分类号 C07D498/04
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