发明名称 |
POPULATIONS OF HEMATOPOIETIC PROGENITORS AND METHODS OF ENRICHING STEM CELLS THEREFOR |
摘要 |
There is described herein a method of enriching a population of stem cells for hematopoietic progenitors. The method comprises inducing hematopoietic differentiation in a population of human embryonic stem cells or human induced pluripotent stem cells; sorting the population based on expression of CD43 and at least one of CD34, CD31 and CD144; and selecting a fraction that is at least one of CD34+CD43-, CD31+CD43- and CD144+CD43-. Also provided are populations of hematopoietic progenitors obtained by the methods described herein. |
申请公布号 |
CA2856322(A1) |
申请公布日期 |
2013.05.30 |
申请号 |
CA20122856322 |
申请日期 |
2012.11.21 |
申请人 |
UNIVERSITY HEALTH NETWORK;SUNNYBROOK RESEARCH INSTITUTE |
发明人 |
KELLER, GORDON;ZUNIGA-PFLUCKER, JUAN CARLOS;KENNEDY, MARION J.;STURGEON, CHRISTOPHER MICHAEL;DITADI, ANDREA;AWONG, GENEVE SHEANDRA |
分类号 |
C12N5/0789;C12N5/071;C12Q1/24 |
主分类号 |
C12N5/0789 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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