| 摘要 |
The invention is related to anti-viral phosphinate compounds of general structure formula Iwherein Ris -C(O)OC-Calkyl, -C(O)OC-Ccycloalkyl, -C(O)OC-Calkyl, -C(O)C-Calkyl substituted with at least one substituent selected from a group comprising halogen, an amino group, phenyl, -C(O)CHC-Ccycloalkyl, Caryl, optionally substituted with a substituent selected from a group of substituents, comprising C-Calkyl and CF, C-Cheteroaryl, comprising from 1 to 4 heteroatoms selected from a group of heteroatoms comprising N and S, optionally substituted with C-Calkyl, -SO-C-Calkyl optionaly substituted with at least a halogen, -C(CH)C=NHC-Calkyl optionally substituted with at least a halogen; Yis O; Zis O; Zis H, (C-C)alkyl, (C)alkenyl or (C)alkynyl; Qis (C-C)alkyl, (C)alkenyl; Zis H; or Qand Zform together a group optionally substituted with C-Calkyl. |
