发明名称 |
BENDAMUSTINE ANIONIC-CATIOINIC CYCLOPOLYSACCHARIDE COMPOSITIONS |
摘要 |
<p>The present invention is directed to pharmaceutical compositions including: (a) bendamustine, (b) a first charged cyclopolysaccharide, and (c) a stabilizing agent which is a second charged cyclopolysaccharide having a charge opposite to that of the first charged cyclopolysaccharide. The composition provides unexpectedly desirable stability in reactive environments such as plasma, coupled with unexpectedly desirable anticancer activity. The compositions are suitable for injection or infusion into patients in need for treatment with bendamustine.</p> |
申请公布号 |
EP2595660(A2) |
申请公布日期 |
2013.05.29 |
申请号 |
EP20110861891 |
申请日期 |
2011.02.23 |
申请人 |
SUPRATEK PHARMA, INC. |
发明人 |
ALAKHOV, VALERY;PIETRZYNSKI, GRZEGORZ;PATEL, KISHORE;POPEK, TOMASZ |
分类号 |
A61K47/40;A61K9/00;A61K31/4184;A61P35/00;C07D235/16 |
主分类号 |
A61K47/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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