<p>Provided is a method of treating a proliferative disease, condition, or disorder in a subject by administering a combination of an inhibitor of p53 and MDM2 binding and an EGFR inhibitor. Various embodiments of the disclosed methods provide a synergistic anti-proliferative or anti-apoptotic effect compared to administration of one agent alone.</p>
申请公布号
EP2596366(A1)
申请公布日期
2013.05.29
申请号
EP20110810417
申请日期
2011.07.21
申请人
ERRICO, JOSEPH P.
发明人
MUGRAGE, BENJAMIN;TURCHI, IGNATIUS;SILLS, MATTHEW;ONG, JANE;ALLOCCO, JOHN;WINES, PAM;BASTOS, MARGARITA;ERRICO, JOSEPH, P.