| 摘要 |
The present invention provides a novel amino compound that blocks the IKur current or the Kv1.5 channel potently and more selectively than other K+ channels. The present invention relates toa benzodiazepine compound represented by General Formula (1):
or a salt thereof,
wherein R 1 , R 2 , R 3 , and R 4 are each independently hydrogen or lower alkyl; R 2 and R 3 may be linked to form lower alkylene;
A 1 is lower alkylene optionally substituted with one or more hydroxyls; and R 5 is an aryl or heterocyclic group, each of which is optionally substituted. |
