摘要 |
It is described a process for the preparation of Drospirenone, a synthetic steroid with progestogenic anti-mineralocorticoid and antiandrogenic activity having the formula 1 shown below, useful in the preparation of contraceptive pharmaceutical compositions, starting from 17±-(3-hydroxypropyl)-6²,7²;15²,16²-dimethylene-5²-androstan-3²,5,17²-triol. |