发明名称 DRUG DELIVERY SYSTEM FOR SUBCONJUNCTIVAL ADMINISTRATION OF FINE PARTICLES
摘要 The present invention provides an excellent drug delivery system to posterior segments. An injection according to the present invention is a subconjunctival injection which comprises fine particles containing a drug and enables the drug to deliver to the posterior segments. The drug can be efficiently delivered to the posterior segments (such as a retina, a choroid and an optic nerve) while scarcely injuring ophthalmic tissues by administering the fine particles containing the drug subconjunctivally Preferred fine particles are made of a synthetic biodegradable polymer, their average particle dispersed in the fine particles uniformly. Preferred diameter is 50 nm to 150 µ m, and the drug is drugs are anti-inflammatories, immunosuppressors, antivirals, anticancer drugs, angiogenesis inhibitors, optic neural protectants, antimicrovials and antifungal .agents.
申请公布号 CA2476935(C) 申请公布日期 2013.05.28
申请号 CA20032476935 申请日期 2003.02.21
申请人 SANTEN PHARMACEUTICAL CO., LTD. 发明人 KUWANO, MITSUAKI;YAMADA, KAZUHITO
分类号 A61K9/08;A61K9/00;A61K9/14;A61K9/16;A61K31/573;A61K47/06;A61K47/32;A61K47/36;A61P27/02;A61P29/00;A61P31/04;A61P31/10;A61P31/12;A61P35/00;A61P37/06 主分类号 A61K9/08
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