| 发明名称 |
SYNTHETIC DOUBLE-STRANDED OLIGONUCLEOTIDES FOR SPECIFIC INHIBITION OF GENE EXPRESSION |
| 摘要 |
The invention relates to oligonucleotide derivatives which are at least partially double stranded and which comprise a 2'5' linked oligonucleotide radical on at last one 3'- end. The invention also relates to the use thereof for targeted inhibition of gene expression.
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| 申请公布号 |
CA2453301(C) |
申请公布日期 |
2013.05.28 |
| 申请号 |
CA20022453301 |
申请日期 |
2002.07.05 |
| 申请人 |
AVENTIS PHARMA DEUTSCHLAND GMBH |
发明人 |
UHLMANN, EUGEN;HUBER, JOCHEN;GUNKEL, NIKI;NEUMANN, SANDRA |
| 分类号 |
C07H21/00;C12N15/09;A61K31/7088;A61K31/7125;A61K38/00;A61K48/00;A61P3/00;A61P9/00;A61P11/06;A61P29/00;A61P31/04;A61P31/12;A61P35/00;C12N15/11 |
主分类号 |
C07H21/00 |
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