发明名称 Pharmaceutical composition having improved solubility
摘要 It is desired to provide a pharmaceutical composition containing a compound represented by formula (I) or a pharmacologically acceptable salt thereof, or a solvate thereof, which exhibits an inhibitory effect on activated blood coagulation factor X (FXa), and is useful as an agent for preventing and/or treating thrombosis, wherein the pharmaceutical composition exhibits favorable dissolution properties. The present invention relates to a solid pharmaceutical composition containing a compound represented by formula (I) or a pharmacologically acceptable salt thereof, or a solvate thereof, wherein the content of the compound represented by formula (I) is 0.5% by weight or more and less than 15% by weight with respect to the total weight of the pharmaceutical composition.
申请公布号 US8449896(B2) 申请公布日期 2013.05.28
申请号 US201113328847 申请日期 2011.12.16
申请人 KAMADA MAKOTO;KIDOKORO MOTONORI;SEKIGUCHI GAKU;DAIICHI SANKYO COMPANY, LIMITED 发明人 KAMADA MAKOTO;KIDOKORO MOTONORI;SEKIGUCHI GAKU
分类号 A61K9/14;A61K9/20 主分类号 A61K9/14
代理机构 代理人
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