发明名称 |
Polymer conjugates of nesiritide peptides |
摘要 |
The invention provides peptides that are chemically modified by covalent attachment of a water-soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of peptide not attached to the water-soluble oligomer.
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申请公布号 |
US8449872(B2) |
申请公布日期 |
2013.05.28 |
申请号 |
US200913119215 |
申请日期 |
2009.09.17 |
申请人 |
ZAPPE HAROLD;BOSSARD MARY J.;NEKTAR THERAPEUTICS |
发明人 |
ZAPPE HAROLD;BOSSARD MARY J. |
分类号 |
A61K47/48;A61K38/12;C07K1/107;C07K14/00;C08G65/48 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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