发明名称 |
Vaccines based on targeting antigen to DCIR expressed on antigen-presenting cells |
摘要 |
The present invention includes compositions and methods for increasing the effectiveness of antigen presentation using a DCIR-specific antibody or fragment thereof to which an antigen is attached that forms an antibody-antigen complex, wherein the antigen is processed and presented by a dendritic cell that has been contacted with the antibody-antigen complex.
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申请公布号 |
US8449888(B2) |
申请公布日期 |
2013.05.28 |
申请号 |
US201113234914 |
申请日期 |
2011.09.16 |
申请人 |
ZURAWSKI GERARD;BANCHEREAU JACQUES F.;KLECHEVSKY EYNAV;ZURAWSKI SANDRA;FLAMAR ANNE-LAURE;BAYLOR RESEARCH INSTITUTE |
发明人 |
ZURAWSKI GERARD;BANCHEREAU JACQUES F.;KLECHEVSKY EYNAV;ZURAWSKI SANDRA;FLAMAR ANNE-LAURE |
分类号 |
A61K39/395;A61K39/12;C07K16/28;C07K16/46 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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