发明名称 |
EXPANDING BONE MARROW-DERIVED IMMUNE REGULATORY CELLS AND IMMUNE REGULATORY B CELLS BY ACTIVATING GPCR19 PATHWAY IN VIVO OR IN VITRO |
摘要 |
<p>PURPOSE: A method for screening a therapeutic agent for treating GPCR19(G-protein coupled receptor 19)-related diseases or a method for analyzing efficiency of a GPCR19 agonist is provided to obtain an anti-inflammatory pharmaceutical composition. CONSTITUTION: A method for screening a therapeutic agent for treating GPCR19-related diseases comprises: a step of administering a physiological activity control material to mammals exclusive of humans; a step of administering a GPCR19 agonist test material to the mammals; and a step of analyzing generation of regulatory B cells in the mammals. The test material is determined as a therapeutic agent for treating GPCR19-related diseases when cell production is increased over a control group.</p> |
申请公布号 |
KR20130054702(A) |
申请公布日期 |
2013.05.27 |
申请号 |
KR20110120247 |
申请日期 |
2011.11.17 |
申请人 |
SNU R&DB FOUNDATION |
发明人 |
SEONG, SEUNG YONG;CHANG, SOOG HEE;KIM, YOUN HEE;KIM, YOUNG JOO;JUNG, HI EUN |
分类号 |
C12Q1/68;A61K31/565 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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