| 摘要 |
FIELD: medicine.SUBSTANCE: invention refers to medicine and veterinary science; it is used in transplantology, traumatology, surgery and oncology, and may be used to fill bone defects. What is described is a bioimplant which represents a donor bone deimmunised with chlorine-containing oxidants, a surface of which is covered with a multifunctional bioactive nanostructured coating (MBNC) of M-Ca-P-C-O-N or M-Ca-CON, wherein M is a metal specified in a group consisting of Si, Ti, Zr, Hf, Nb, Ta, and colonised by recipient's mesenchymal stem cells (MSC).EFFECT: MBNC-coated bioimplant is in line with the anatomical and morphological characteristics of the replaced bone, provides cell adhesion, no transplant rejection, accelerated formation of connective tissue and callus.8 dwg, 1 ex |
| 申请人 |
FEDERAL'NOE GOSUDARSTVENNOE BJUDZHETNOE UCHREZHDENIE "ROSSIJSKIJ ONKOLOGICHESKIJ NAUCHNYJ TSENTR IMENI N.N. BLOKHINA" ROSSIJSKOJ AKADEMII MEDITSINSKIKH NAUK (FGBU "RONTS IM. N.N. BLOKHINA" RAMN);FEDERAL'NOE GOSUDARSTVENNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA "NATSIONAL'NYJ ISSLEDOVATEL'SKIJ TEKHNOLOGICHESKIJ UNIVERSITET "MISIS" (NITU "MISIS") |
发明人 |
ANISIMOVA NATAL'JA JUR'EVNA;KISELEVSKIJ MIKHAIL VALENTINOVICH;SHTANSKIJ DMITRIJ VLADIMIROVICH;DONENKO FEDOR VITAL'EVICH;SITDIKOVA SURIJA MANSUROVNA;RESHETNIKOVA VERA VLADIMIROVNA;LEVASHOV EVGENIJ ALEKSANDROVICH;KORNJUSHENKOV EVGENIJ ALEKSANDROVICH;KULESHOVA JANA ALEKSANDROVNA;DAVYDOV MIKHAIL IVANOVICH |
