| 发明名称 |
METHOD FOR PRODUCING AND PURIFYING IL-29 |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide expression vectors and methods using an E. coli expression system for the large scale production of IL-29. <P>SOLUTION: The invention relates to IL-29 with specific changes in nucleotides in order to optimize codons and mRNA secondary structure for translation in E. coli, and methods of producing, purifying and pegylating an IL-29 polypeptide. <P>COPYRIGHT: (C)2013,JPO&INPIT |
| 申请公布号 |
JP2013099337(A) |
申请公布日期 |
2013.05.23 |
| 申请号 |
JP20120284581 |
申请日期 |
2012.12.27 |
| 申请人 |
ZYMOGENETICS LLC;BRISTOL-MYERS SQUIBB CO |
发明人 |
ZAMOST BRUCE L;LEE GEOFFREY F;DEDINSKY ROBERT M |
| 分类号 |
C12P21/02;C07K14/54;C12N15/09 |
主分类号 |
C12P21/02 |
| 代理机构 |
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