发明名称 |
LONG INTERFERING DSRNA SIMULTANEOUSLY INDUCING AN IMMUNE REACTION AND THE INHIBITION OF THE EXPRESSION OF TARGET GENES |
摘要 |
<p>The present invention relates to a long interfering dsRNA (liRNA) capable of promoting an immune reaction as well as inhibiting the expression of specific RNAi-mediated target genes, and to uses thereof. More particularly, the present invention relates to a long interfering dsRNA capable of inducing the expression of interferon-beta by stimulating, depending on a structure, a protein kinase R (PKR) path as well as inhibiting the expression of specific target genes through an RNA-interfering reaction through a specific sequence.</p> |
申请公布号 |
WO2012165854(A9) |
申请公布日期 |
2013.05.23 |
申请号 |
WO2012KR04259 |
申请日期 |
2012.05.30 |
申请人 |
RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY;LEE, DONG KI;CHANG, CHAN IL |
发明人 |
LEE, DONG KI;CHANG, CHAN IL |
分类号 |
C12N15/113;A61K31/7105;A61K48/00;A61P31/12;A61P35/00 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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