| 发明名称 |
SUBSTITUTED ISOQUINOLINES AND THEIR USE AS TUBULIN POLYMERIZATION INHIBITORS |
| 摘要 |
The present invention relates generally to substituted isoquinolines and their use as tubulin polymerization inhibitors. In particular, the invention relates to substituted isoquinolines which possess useful therapeutic activity, use of these compounds in methods of therapy and the manufacture of medicaments as well as compositions containing these compounds.
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| 申请公布号 |
US2013131018(A1) |
申请公布日期 |
2013.05.23 |
| 申请号 |
US201113701917 |
申请日期 |
2011.06.01 |
| 申请人 |
LEBLOND BERTRAND;TAVERNE THIERRY;BEAUSOLEIL ERIC;CHAUVIGNAC CEDRIC;CASAGRANDE ANNE-SOPHIE;DESIRE LAURENT;EXONHIT S.A. |
发明人 |
LEBLOND BERTRAND;TAVERNE THIERRY;BEAUSOLEIL ERIC;CHAUVIGNAC CEDRIC;CASAGRANDE ANNE-SOPHIE;DESIRE LAURENT |
| 分类号 |
C07D217/20;A61K31/437;A61K31/472;A61K31/4725;A61K31/675;A61K45/06;C07D401/10;C07D405/10;C07D498/04;C07F9/62 |
主分类号 |
C07D217/20 |
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