发明名称 |
CHIMERIC NON-INTEGRATING LENTIVIRAL GENOMES AS VACCINES AGAINST HIV-1 |
摘要 |
The present invention relates to nucleic acids containing chimeric non-integrating retrovirus genomes including the long terminal repeat (LTR) sequences 5' and 3' of the caprine lentivirus, the caprine arthritis/encephalitis virus (CAEV), or another retrovirus that does not integrate into human cells, and at least one viral gene of another retrovirus. The invention also relates to a vector containing such a nucleic acid, to an immunogenic or vaccine composition containing said vector or said nucleic acid, and to the use thereof for treating and/or preventing an infection by a retrovirus or disease induced by a pathogen. |
申请公布号 |
WO2013037841(A3) |
申请公布日期 |
2013.05.23 |
申请号 |
WO2012EP67863 |
申请日期 |
2012.09.12 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S);CHEBLOUNE, YAHIA;ALDEBERT, DELPHINE;ARRODE-BRUSES, GERALDINE |
发明人 |
CHEBLOUNE, YAHIA;ALDEBERT, DELPHINE |
分类号 |
C12N15/867;A61K39/21;C07K14/155;C07K14/16 |
主分类号 |
C12N15/867 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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