| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a small molecule modulator for treating diseases, including cancers such as lung, breast, colon, and/or prostate cancers as well as other diseases that are associated with Trp-p8 expression. <P>SOLUTION: There is provided a compound represented by formula 1, (wherein R<SB POS="POST">1</SB>is selected from H, alkyl, aryl, and the like; or R<SB POS="POST">1</SB>and R<SB POS="POST">2</SB>can form a cyclic group or a heterocyclic group together with a nitrogen group; R<SB POS="POST">2</SB>is selected from aryl, and arylalkyl; R<SB POS="POST">3</SB>is selected from alkyl, and the like; R<SB POS="POST">4</SB>is selected from H, alkyl, heteroalkyl, and the like; and R<SB POS="POST">3</SB>and R<SB POS="POST">4</SB>form an aliphatic amine together with a nitrogen group). <P>COPYRIGHT: (C)2013,JPO&INPIT |
