N-SUBSTITUTED AMINOBENZOCYCLOHEPTENE, AMINOTETRALINE, AMINOINDANE AND PHENALKYLAMINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY

摘要

The present invention relates to N-substituted aminobenzocycloheptene,aminotetraline, aminoindane and phenalkylamine derivatives of the formula (I),(II), (III) or (IV) or a physiologically tolerated salt thereof. The invention relates topharmaceutical compositions comprising such N-substituted amino-benzocycloheptene,aminotetraline, aminoindane and phenalkylamine derivatives, and the use of such N-substituted aminobenzocycloheptene,aminotetraline, aminoindane and phenalkylamine derivatives for therapeutic purposes. The N-substituted aminobenzocycloheptene,aminotetraline, aminoindane and phenalkylamine derivatives are GlyT1 inhibitors.