发明名称 BINDING MOLECULES FOR BCMA AND CD3
摘要 The present invention relates to a binding molecule comprising a first and a second binding domain, wherein the first binding domain is capable of binding to epitope clusters of BCMA, and the second binding domain is capable of binding to the T cell CD3 receptor complex. Moreover, the invention provides a nucleic acid sequence encoding the binding molecule, a vector comprising said nucleic acid sequence and a host cell transformed or transfected with said vector. Furthermore, the invention provides a process for the production of the binding molecule of the invention, a medical use of said binding molecule and a kit comprising said binding molecule.
申请公布号 WO2013072415(A1) 申请公布日期 2013.05.23
申请号 WO2012EP72730 申请日期 2012.11.15
申请人 AMGEN RESEARCH (MUNICH) GMBH;BOEHRINGER INGELHEIM INTERNATIONAL GMBH 发明人 KUFER, PETER;RAUM, TOBIAS;HOFFMANN, PATRICK;KISCHEL, ROMAN;LUTTERBUESE, RALF;RAU, DORIS;ADAM, PAUL;BORGES, ERIC;HEBEIS, BARBARA;HIPP, SUSANNE
分类号 C07K16/28;A61K39/395;A61P35/02;A61P37/00 主分类号 C07K16/28
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