| 发明名称 |
NUCLEIC ACID DELIVERY COMPOSITIONS AND METHODS OF USE THEREOF |
| 摘要 |
<p>This disclosure relates to nucleic acid constructs modified to have a reduced net anionic charge. The constructs comprise phosphotriester and/or phosphothioate protecting groups. The disclosure also provides methods of making and using such constructs.</p> |
| 申请公布号 |
EP2438079(A4) |
申请公布日期 |
2013.05.22 |
| 申请号 |
EP20100783926 |
申请日期 |
2010.06.01 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
DOWDY, STEVEN, F.;MEADE, BRYAN;GOGOI, KHIRUD |
| 分类号 |
C07H21/02;A61K31/7105;A61K48/00;C07H19/16;C12N15/113 |
主分类号 |
C07H21/02 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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