Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds are provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.
申请公布号
EP2498609(A4)
申请公布日期
2013.05.22
申请号
EP20100830879
申请日期
2010.11.15
申请人
RECEPTOS, INC.
发明人
BOEHM, MARCUS, F.;MARTINBOROUGH, ESTHER;BRAHMACHARY, ENUGURTHI;MOORJANI, MANISHA;TAMIYA, JUNKO;HUANG, LIMING;YEAGER, ADAM, RICHARD